MATERIA MEDICA AND THERAPEUTICS. 171 



tal and motor activity, stimulates voso-motor nerves, etc., and de- 

 presses sensation. Intoxication or complete and heavy sleep are 

 caused by it according to the size of the dose, in animal as in 

 man. 



Toxicology. — Indian Cannabis is supposed to be a non-toxic 

 drug, but the writer advises that not over two ounces of the 

 fluid extract or two drachms of the solid extract (except in teta- 

 nus) be given within eight hours, as disagreeable if not alarming 

 symptoms may arise. 



Full doses cause drowsiness, sleep, stupor and coma accord- 

 ing to quantity. Respirations become slow and shallow, pulse 

 weak and accelerated. The condition may last for two or three 

 days, during which time the animal is in a more or less anaesthetic 

 state, refuses or rather doesn't notice food and frequently the 

 bowels are constipated. 



Excessive quantities (j4 pint of the fluid extract) has caused 

 the death of several horses to the writer's knowledge. 



Antidotes. — Lemon juice, vinegar and citrated caffeine 

 (grs. xv. to 3j. for horse, every 3 or 4 hours). 



Uses. — Excellent in spasmodic colic. For spasmodic colic: 



5 Fl. ex. cannabis ind., 3 j. 



Fl. ex. hyoscyami, 3 j. 



Tr. capsici, 3 ij- 



Spts. ammon. arom. 3 'j- 



Ac. salicylici 3 iij. 



M. Sig. — Give one-half at a dose in a pint of water, and repeat in $4 

 of an hour if necessary. 



In tetanus use large doses, an Englishman claims to have 

 cured 50 per cent of his cases with it ; is an excellent sedative 

 and anodyne to the urinary apparatus for dysuria and retention 

 of urine, due to spasm of the sphincter. 



In small doses (one to two drachms for the horse) given 

 every 3 hours, is a useful adjunct to regular treatment for those 

 patients (suffering from pneumonia, etc.) who seem to be melan- 

 choly, without ambition, won't eat, etc. 



COCA— COCA. 



The Leaves of Erythroxylon Coca. 



Coca should not be confounded with Cocoa, a beverage pre- 

 pared from the seeds of Theobroma Cacao, the chocolate-tree. 



