MATERIA MEDICA AND THERAPEUTICS. 205 



For Azoturia : 



IJ Tr. arnicae rad., J vj. 



Fl. ex. colchici sem., J jss. — 3 iij. 



Fl. ex. pilocarpi, 3 vj. 



Spts. aeth. nit., 3 vj. 



Aquae qs. ad., 3 xxiv. 



M. Sig. — 2 ozs. every 3 or 4 hours in % pint of water. 



Pilocarpine hydrochlorate 1 to 2 grs. to the ounce of dis- 

 stilled water may be used as a myotic in place of eserine. 



It is also used in small repeated doses to stimulate the secre- 

 tion of milk when it is failing. 



In very small doses (V3 usual dose) it has the property of 

 lessening the excessive secretion of saliva and sweat 



The pilocarpine hydrochlorate may be used as antidote to 

 belladonna or atropine poisoning. 



PHYSOSTIGMA— CALABAR BBAN. 



EXTRACTUM PHYSOSTIGMATIS. 



Dose. — Horse, 3 to 8 grs. ; dogs, fo to y 2 gr. f fi 



TINCTURA PHYSOSTIGMATIS. ("£5%). - - 



Dose. — Horse, 2 to 6 drs. ; dogs, 2 to 20 ms. 



EXTRACTUM PHYSOSTIGMATIS FXUIDUM Fid. B.Vt. of PhyS- 



ostigma (not official). 



Dose. — Horses, y 2 to 2 drs. ; cattle 1 to 3 drs. ; of the pow- 

 dered bean or seed 1 to 2 drs., but 1 dr. of the powder or Fid. 

 Ext. is the average dose. 



Composition. — Contains three alkaloids, Physostigmine or 

 Eserine, Calabarine and Eseridine. Physostigmine is the only 

 one used. 



physosTigminaE sulphas. — Occurs as a white or yellowish 

 white powder very soluble in water and alcohol. 



Preferred to the salicylate on account of its greater solu- 

 bility. 



physostigminae salicylas. — Occurs in colorless, shining ' 

 crystals, both salts turning reddish on long exposure to air and 

 light, odorless, bitter taste and neutral reaction, soluble in 130 

 parts of water and in 12 parts of alcohol at 159° F. Both are 

 extremely hygroscopic, the sulphate spoils very quickly. 



Dose of both salts is the same. 



