1° 



208 SYNOPSIS OF VETERINARY 



when the intestinal murmur cannot be heard, showing paralysis 

 of the bowels. 



Eserine is very beneficial in flatulent colic ; give i gr. dose 

 hypodermically or intratracheally, then repeat with y-t gr. dose in 

 20 or 30 minutes if necessary or give 1^-2 gr. at once if the horse 

 is strong, (best to combine it with Pilocarpine). 



In "choke" give the usual cathartic dose (1^2 gr. for horse, 

 2 to 3 grs. for cattle) after administering a few ounces of oil. 



In Parturient Paresis, Eserine often proves of great value ; 

 it should be followed by strychnine. 



It should be tried in invagination of- the bowels. 



LOBEUA— INDIAN TOBACCO. 



TINCTURA LOBEXIAE— ^Sefc) . 



Dose. — Dogs, 3 ms. to 15 ms., y 2 to 1 dr. as an emetic. 



Extractum lobeliae fluidum — Fid. Ext. of Lobelia. 



Dose. — Horse, 1 dr. to 1 oz. ; dog, J4 to 10 ms., as emetic 20 

 to 30 ms. 



Composition. — Activity of lobelia is due to its alkaloid, Lo- 

 beline; also contains lobelic acid, etc. 



Antagonists and Incompatibles. — Caustic alkalies ; its de- 

 pressing effects, by digitalis, belladonna, ergot, and other vaso- 

 motor excitants, by alcohol, ether, ammonia, etc. ; on the nervous 

 system of animal life, strychnine, picrotoxin, thebaine, etc. 



Synergists. — The motor depressants. 



Physiological Actions. — It has an acrid nauseous taste and 

 very unpleasant odor; it is expectorant, diaphoretic, purgative, 

 emetic, antispasmodic, and narcotic ; it excites an abundant flow 

 of saliva, much gastric mucus, profuse urination and sweating, 

 with great nausea, vomiting and great depression, the action of 

 the heart is enfeebled, the blood pressure at first increased, soon 

 falls, muscular debility, reduced temperature, then coma and 

 death by paralysis of the respiratory centers, the motor nervous 

 system is chiefly affected, especially the medulla oblongata and 

 the nucleus of the pneumogastric contained therein. 



Uses. — Lobelia is very useful in asthma in dogs or man, 

 combined with belladonna and gelsemium ; in heaves in horses, 



