MATERIA MEDlCA AND THERAPEUTICS. 221 



sheep the salines are preferred ; dogs, 2 to 30 grs. up to 1 dr. ; 

 swine, 2 to 4 drs., as a bitter tonic jV to }i these doses. 



The dose of aloin for horses is 3 to 4 drs. 



Aloin, theoretically is many times stronger than aloes, but 

 practically it is only twice as strong. So that the dose may be 

 figured as j4 that of aloes. 



It should be combined with the usual synergist and given 

 in capsule or bolus. 



Merck & Co's Aloin is recommended by the writer. 



Physiological Actions. — Aloes is purgative, acting chiefly on 

 the large intestines ; small doses are bitter tonics ; applied exter- 

 nally it is stimulant and desiccant; it stimulates both peristalsis 

 and secretion, increases secretion of bile ; is also diuretic ; the 

 barbadoes is the most active and uniform in its effects. 



It should be kept in lumps in tin cans or other good con- 

 tainers, only being powdered for immediate use ; in melting aloes 

 don't let the temperature rise above 120 degrees, as it impairs 

 the activity by converting the active aloin into inert resin. 



Aloes operates in from 12 to 24 hours after administration ; 

 don't repeat an aloetic purge until 48 hours have elapsed. 



If aloes does not cause catharsis in about 15 hours, the 

 horse should be exercised, but returned, to his stall as soon as 

 the desired effect is evident. ""~ -~- 



If it fails to act in 24 hours, linseed oil may be given. 



Preparation, by feeding several bran mashes is advisable 

 when possible, previous to the administration of an aloetic purge 



Uses. — In dyspepsia with capricious appetite, irregularity of 

 the bowels, hide-bound horses ; worms ; is used in colics, both 

 spasmodic and flatulent, for overloaded condition of the bowels ; 

 to promote excretion of waste products from the bowels and the 

 blood, and consequently relieve febrile symptoms ; rheumatic 

 attacks, skin irritation, swollen limbs and inflamed joints ; in 

 lymphangitis to prevent and aid in curing. By attracting the 

 blood to the bowels, it is useful in congestion or inflammation of 

 the brain and spinal cord ; full doses being necessary ; in paralysis, 

 paraplegia or hemiplegia or reflexed paralysis due to indigestion 

 give a full purgative. 



Aloes should not be used in irritation or inflammation of the 

 alimentary canal or piles. It is not advisable to give an aloetic 



