MATERIA MEDICA AND THERAPEUTICS. 235 



Actions. — On the heart and circulation it acts like digitalis; 

 large doses cause vomiting' and purging, is used chiefly for its 

 expectorant and diuretic effects; should not be used in nephritis 

 as it is too irritating. 



There is also a tincture ($5%), a vinegar ( ioj%) and a com- 

 pound syrup of squills (8%). Doses for dogs, 5 to 30 ms. 



OLEUM RUTM—OIL OF RUE. 



OLEUM SABINE— OIL OF SAVINE. 



These are used chiefly in human practice as Emmenogogues, 

 and abortifacients. 



Dose. — Bitches, 1 to 5 ms. ; mares, 1 to 3 drs. ; their combina- 

 tion with aloes and myrrh make a powerful abortifacient. They 

 are irritating and should be well diluted in oil. They may be 

 used in moderated repeated doses to bring on delayed oestrum. 

 Savine is the safest. 



COUNTER-IRRITANTS. 



CANTHARIS— CANTHARIDES. 



Synonyms. — Spanish Fly, Blister Beetles, 

 putvis cantharis — Powdered Cantharides. 

 Dose. — Horses and cattle, 5 to 30 grs. ; sheep and swine, 4 

 to 8 grs. ; dogs, % to 2 grs. 



tinctura cantharidis. — Tincture of Cantharides. (sfo.) 

 Horses and cattle, 1 to 4 drs. ; dogs, 2 to 10 ms. 



Actions. — Externally, is irritant, rubefacient, vesicant, ac- 

 cording to the strength used, it produces water blisters ; counter- 

 irritant, etc. 



Internally is irritant, large or undiluted doses cause gastro- 

 enteritis; small doses stimulate the genito-urinary tract, hence, 

 is diuretic and aphrodisiac. 



Full doses cause inflammation, strangury and hsematuria. 



Use's. — Internally is seldom used except in incontinence of 

 urine from debility or partial paralysis of the bladder, more rarely 

 to encourage "heat." 



