246 SYNOPSIS OF VETERINARY 



SUPRARENALIN SOLUTION, ( I to IOOO) dogS, 5 to 30 HIS J also 



for local use. 



suprarenal gland dried, i part equals 5 of fresh gland. 



Dose. — Dogs, 2 to 8 grs. 



Extract suprarenal capsule (Merck & Co.) used locally 

 in 6 to 30 per cent solutions, or intravenously in I per cent solu- 

 tion in doses of y 2 to 2 drs. for dogs, horses, Ij4 to 3 ozs. 



Solutions should be prepared fresh each time with newly 

 sterilized distilled water. 



suprarenal gland, desiccated' (Parke, Davis & Co.) 



Dose. — Dogs, 2 to 8 grs. ; horses, y 2 to 2 drs. ; also used 

 locally in about 6 per cent solution. 



Supplied in tablets and capsules, 2 grs. each and in bulk. 

 . Physiological Actions. — The suprarenals ; represented by the 

 above preparations, cause the following effects. 



1. Rise of blood pressure through the peripheral stimula- 

 tion of the vaso-constrictor mechanism, secondary to this rise of 

 pressure there is a stimulation of the vagus (inhibitory apparatus) 

 and, consequently, a slowing of the heart. 



2. A digitalis action on the heart (strengthening and slow- 

 ing-) 



3. A depression of the respiratory center. 



4. Dilation of the pupil, through direct stimulation of the 

 iris muscular fibres. 



5. Locally, extreme contraction of capillaries and the small 

 veins and arteries. 



Therapy.- — In veterinary practice the greatest use for the 

 drug is in operations concerning the mucous membranes of the 

 eyes and nostrils and to render the field for the various neurec- 

 tomies, bloodless. 



In the former a solution of Adrenalin chloride 1 to 1000 or 

 1 to 2000 is applied direct to the membrane, resulting in blanching 

 of it and thus rendering the part bloodless. 



For neurectomy, the drug is best used 1 to 1000, a little 

 [y 2 dr.) injected into the substance of the skin and some (J4 to 

 1 dr. ) under it, allowing about five minutes to elapse before using 

 the knife. 



