252 SYNOPSIS 01? VETERINARY 



In addition to the febrile reaction, note the size, appearance, and 

 duration of any local swelling at the point of injection. 



Note the general condition and symptoms of the animal both 

 before, during, and after the test. After four or five days the 

 injection may be repeated, if the reaction from the first injection 

 is not entirely satisfactory. 



Keep the solution in a sealed bottle in a cool place. 



The experiments conducted at the Veterinary Experiment 

 Station of the Bureau of Animal Industry and elsewhere, have 

 shown as quoted below : 



I. — "That the injection of the Malleine causes a rise in the 

 temperature of 2° to 5 F. in all horses affected with glanders 

 except sometimes in well developed or advanced cases of the 

 disease, already having a temperature of 102 F. or above. In 

 no case has the maximum temperature of a glandered horse, 

 following the injection, fallen below 103° F. 



2. — "On the glandered horse an abrupt, hard, painful swell- 

 ing, 4 to 10 inches in diameter, occurs at the point of injection. 

 This generally begins to appear 2 to 4 hours after the injection, 

 continuing on the next day and increasing in size, from I to 

 3 days, disappearing again in from 3 to 9 days afterwards. 



3. — "Subsequent injections in glandered horses gave a similar 

 reaction, although frequently less marked. 



{For more details in the use of the various serums, the 

 reader is referred to the excellent work of Prof. Veranus A. 

 Moore, "The Pathology and Differential Diagnosis of Infectious 

 Diseases of Animals.") 



DIRECTIONS FOR DISGUISING THE COLOR, TASTE 

 AND ODOR OF MIXTURES. 



It is frequently desirous to give a pleasant taste and odor 

 to nauseous mixtures, especially when they are to be administered 

 to animals that vomit, particularly the dog, whose stomach is 

 very easily irritated by nauseous mixtures. 



Color is frequently added for its pleasing effect to the eye. 



And again the disguising of our mixtures often becomes 

 necessary from a business standpoint, as a protection against the 

 layman who is ever ready to usurp our remedies. 



