MOLDS AND YEASTS AND DISEASES CAUSED BY THEM 247 



is rare, but several cases have been observed. Inoculation of 

 animals (mice, guinea-pigs, puppies, rabbits) is sometimes success- 

 ful, and generalized thrush has followed intravenous injection of 

 young rabbits. The fungus seems to exert some poisonous action, 

 in addition to the mechanical effect upon the tissues. 



Pig. 99. — Scutulum of favus on the arm of a man. {After Plaut.) 



Monilia Psilosis.- — Ashford"^ has found a yeast-like organism 

 on the tongue and in the feces of persons suffering from sprue and 

 in collaboration with Michel has demonstrated the presence of 

 a complement-fixation reaction between the blood of sprue pa- 

 tients and an antigen prepared from cultures of this organism. 

 The cultures are made on acid glucose agar or on Sabouraud's 

 medium. Sprue is a chronic disease characterized by recurrent 

 attacks of diarrhea, with foamy, whitish and bulky stools, progres- 

 sive emaciation and weakness. The subject requires further 

 investigation before the causal relation of Monilia psilosis to 

 the disease can be accepted as established. 



Achorion Schoenleinii. — The fungus of favus was discovered by 



Schoenlein in the skin lesions of this disease in 1839, two years 



after the recognition of Botrytis bassiana as the cause of mus- 



cardine. Remak in 1845 grew the mold on slices of apple and 



> 1 Ashford, Amer. Journ. Med. Sciences, 1916, 151, p. 520; *«<'•, iQi?, IS4.P- iS7 



