MASTIGOPHORA 



415 



Kala-Azar is endemic in tropical Asia and northeast Africa 

 where it occurs among the poorer class of people, living in squalor 

 It is characterized by irregular fever, weak- 

 ness and cachexia and especially by enor- 

 mous enlargement of the spleen, often of 

 the liver also. It is frequently fatal. 

 Dogs and monkeys are susceptible to in- 

 oculation. 



Leishmania Tropica. — This organism 

 was first accurately described by J. H. 

 Wright,^ who found it in great abundance 

 in the lesion known as Aleppo boil, Delhi 

 boil or tropical ulcer. The parasites occur 

 within the endothelial cells within the lesion and are very 



Pig. 172. — Leishtnania 

 donovani, various forms 

 observed in artificial cul- 

 ture. {From Doflein after 

 Chalterjee.) 



Fig. 173. — Leishmania tropica. Smear from a Delhi boil. X ISOO. (After 



J. H. Wright.) 



numerous. Leishmania tropica resembles L. donovani very 

 closely except in its pathogenic properties. Cultures on blood- 

 ^Journ. Med. Rsch., 1903, Vol. X, pp. 472-482. 



