SPOROZOA 



445 



segment. The estivo-autumnal malaria caused by PI. falci- 

 parum shows a somewhat irregular and not very characteristic 

 fever curve, but usually there is fever every day (quotidian fe- 

 ver). The tertian fever due to infection with PI. vivax is char- 



PiG. 210. — Plasmodium malaria. Stages of the asexual cycle in the circulating 

 blood. Note the absence of granulation from the hemoglobin' and the uniform size 

 of the red blood cells. X2200. (After Doflein.) 



acterized by febrile attacks recurring at intervals of 48 hours and 

 bearing a very definite relation to the asexual cycle of the para- 

 site." The segmentation of the plasmodium is coincident with 



Pig. 211. — Plasmodium malaria. Sexual cells in the circulating blood. A, 

 Young gametocyte. - B, Full-grown macrogametocyte. C, Pull-grown microgame- 

 tocyte. X2200. (After Doflein.) 



% 



th^ chill and the rise in the patient's temperature. In quartan 



malaria due to infection with PI. malaria, the fever recufs at 



i intervals of 72 hours, again at the stage of segmentation in the 



asexual cycle of the parasite. Obviously an association of two 



