440 



SPECIFIC MICRO-ORGANISMS 



granulation of the erythrocytes. Why the cells containing the 

 larger forms should remain in the internal capillaries of the body 

 is not definitely known. 



Pig. 201.- — Plasmodium falciparum. Stages in the development of the gametocytes 

 (crescents). X2ioo. (After Doflein.) 



The gametocytes develop by the growth of ordinary merozoits, 

 which become erescentic early in their development and differen- 



F enp e c I \P em e c ,ff''' 



Fig. 202. — Sections through the stomach wall of Anopheles showing stages in 

 the development of PI. falciparum. A , Fixed a few hours after the infective feeding, 

 showing ookinetes within the lumen and two in the cuticula of the epithelium. B, 

 Fixed a few days after the infective feeding, showing the partly grown oocyst in the 

 stomach wall. F, Fat surrounding the stomach; em, tunica elastico-muscularis; e, 

 epithelium; c, cuticula; I, lumen of stomach. {From Doflein after Grassi). 



tiated into deeply staining macrogametocytes and pale-staining 

 microgametocytes. These are produced especially in the bone 

 marrow and they circulate in the peripheral blood. Further 



