CHANGES IN NON-PREGNANT UTERUS 



83 



confined to the epithelium believe that the lost cells are replaced by 

 multiplication of the remaining cells. Mandl, for example, describes 

 various stages of mitotic division in the cells of the epithelium at 

 this stage. But this author is of opinion that the epithelia of the 

 •glands assist in the process of renewal. Gebhard describes the 

 epithelium, -which had been lifted from its bed by the blood in the 

 hsematomata, as sinking back to its former position, such cells as 

 were lost being regenerated by multiplication of the others. 



The restoration of the mucosa is accompanied by a decrease in 

 the size of the blood-vessels, and an absorption of the blood which 



Fig. 12. — Section through the human uterus during the recuperation stage. 



(From Sellheim.) 



remains extravasated in the stroma. As to how the blood is 

 absorbed has not been determined in the human female. This is a 

 question which will be discussed in considering the regeneration stage 

 in monkeys and in the lower Mammals. It is stated that new 

 capillaries are formed after the close of the destruction.^ • 



It has already been mentioned that, according to Lipes,^ the 

 constructive stage commences as soon as repair is completed. There 

 is undoubtedly glandular development which may possibly be 

 comparable to what occurs during the post-oestrous or pseudo- 



1 Geist, " Untersuchungen iiber die Histologie der Uterusschleimhaut," 

 Arch. f. Mikr. Anat, vol. Ixxxi., 1913. See also Ooryllos, Eevue de Oynwcol, 

 vol. xviii. and vol. xxvii. 



2 Lipes, loc. dt. 



