33 



The tertian parasite is an irregular and 

 flimsy-looking body, and the medium sizes may 

 show several pseudopodia (Fig. 4). Pigment 

 is scattered throughout and is actively motile, 

 while the quartan parasite is oval or globular, of 

 compact appearance, with darker, coarser pig- 

 ment, shewing but slow motion (Fig. 4). 



The enlargement of the cell in which the 

 simple tertian lies is- also very characteristic. 



In a well-stained specimen we have the 

 further characteristic differences. 



1. Simple Tertian. — The cell is dotted all 

 over with fine red granules (SchOffner's dots), 

 these cells strike the eye during the microscopic 

 examination and are diagnostic (Fig. 4). 



2. Malignant Tertian. — In specimens deeply 

 stained with Romanowsky, the malignant tertian 

 parasite also produces changes in the red cell 

 (Fig. .4). These consist of coarse dots or 

 clefts, especially around the parasite. They are 

 few in number and are equally characteristic of 

 this parasite. Their appearance is quite different 

 from Schuffner's dots. 



Maurer recommends the following method 

 of developing them : — 



10 drops of methylene blue (stock solution) 



-I- 25 c.c. of tap water. 

 15 drops of eosin (stock solution) -f 25 c.c. 

 of water. 

 Mix and stain for five minutes ; shake actively 

 the whole time. 



3. Quartan. — The red cell shows no altered 

 staining ^ characters, but it may appear even 

 smaller than normal. The parasite is not irregu- 

 lar in shape, but compact, oval, or globular. (In 



D 



