302 



Subcutaneously, qiiiniae appears in the urine in 

 twelve to twenty minutes. 



3. Duration of Elimination — 



According to Garofalo it lasts one-and-a-half 



to seven and three-quarter hours. 

 According to Dietl it lasts forty-eight hours. 

 According to Byasson it lasts seventy-two hours. 

 According to Personne it lasts eight days. 



4. The Acme of Elimination — 



According to Thau and Kerner after the first six 

 hours. 



According to Garofalo after the first one-and-a- 

 half to four hours. 



According to Kleine after the first three to 

 six hours. 



5. Hypodermic Injection. — Garofalo states 

 that the elimination is rapid, and that larger doses 

 can be accumulated in the blood in a shorter time 

 by this method than by doses given by the mouth, 

 while Kleine states that the absorption by this 



"method is slow. Kleine's figures will be given 



