309 



Liver. — The pigment is found mainly in 

 the periphery of the lobules, and pigment in 

 the form of blocks in the perivascular con- 

 nective tissue. 



The capillaries are much dilated, and the 

 epithelium contains blocks of pigment. Atrophy 

 of the liver cells and their nuclei occurs. 



Bone Marrow. — The marrow of the long 

 bones is usually red, due to a large develop- 

 ment of haematoblastic tissue. Normoblasts are 

 common. 



Pigment disappears rapidly from the bone 

 marrow. 



LITERATURE 



Marchiafava and Bignami. Twentieth Century Pvactice 

 of Medicine. Malaria. Vol. XIX. S. Low, Marston and Co. 

 This comprehensive and learned treatise is incomparably the 

 best in the English language, dealing with all aspects of 

 malaria and also blackwater fever. 



