326 



haemogregarines, the sexual and asexual cycles 

 occur in the same animal. The cycle of develop- 

 ment is as follows : — 



(i) Sexuals Form or Schizonts. — These are 

 endoglobular, four to eight m in length. Increase 

 in size takes place, and eventually they become 

 spherical and divide into a number of segments 

 (schizonts). According to some observers seg- 

 menting forms are only found in the spleen. 



(ii) Sexual Forms. — Free in the plasma, 

 twelve to fifteen m long. These are male and 

 female, and are characterized by the same general 

 differences as other gametes ; the male mikrogame- 

 tocyte is slender and finely granular ; the female 

 makrogametocyte is fat and coarsely granular. 



(iii) A mikrogamete in the form of a small 

 mass of chromatin separates off and fertilizes 

 the (now) makrogamete. 



(iv) A zygote results, which is at first motile. 

 This becomes encysted as the 



(v) Oocyst, which is found in the epithelial 

 cells of the intestine. This passes out eventually 

 in the faeces of the frog. Sporoblasts are formed 

 as in the malarial cycle, and from these result 



(vi) Sporozoits. — These would gain access to 

 a fresh frog which had swallowed an oocyst. 

 HiNTZE has shewn that frogs confined in pools are 

 especially liable to infection. 



2. H. splendens (~ Dactylosoma splendens). 

 — Found in the blood of R. esculenta. 



The following forms are figured by Labbe 

 (Fig. 71) :— 



(i) Amoeboid forms. 



(ii) Forms resembling in shape a finger- 

 glove. 



