CHEMISTRY OF THE LEUCOMAINES. 335 



50°, and the acid syrupy residue is extracted with 99 

 per cent, alcohol ; the alcoholic extract is in turn 

 evaporated in a vacuum, and the residue taken up with 

 warm alcohol of the same strength. The filtered alcoholic 

 solution is set aside for twenty-four hours, and any deposit 

 which forms is removed by filtration ; ether (65°) is then 

 added as long as a precipitate continues to form, and the 

 whole is again allowed to stand for twenty-four hours. 

 The ether-alcoholic filtrate from this precipitate is evapo- 

 rated first on the watfir bath, and finally in a vacuum ; 

 the slight residue obtained contains a small quantity of 

 basic substances possessing an odor of hawthorn. 



The syrupy precipitate produced by the ether partially 

 crystallizes on standing ; a little absolute ether is then 

 added, and after standing several days more the liquid is 

 separated by means of an aspirator from the deposit of 

 crystals (A). These are first washed with 99 per cent, 

 alcohol, and then extracted with boiling 95 per cent, 

 alcohol. The alcoholic solution, concentrated by evapora- 

 tioji, gives, on cooling, a deposit of lemon-yellow-colored 

 crystals of xantho-ci'eatinine (B), from the mother-liquor 

 of which there separates a crop of new crystals (C). The 

 residue of the crystals (A) left after treatment with the 

 boiling 95 per cent, alcohol is extracted with boiling water, 

 which afterward gives a slight deposit of yellowish-white 

 crystals of amphi-creatine (D). The aqueous mother-liquors 

 on concentration yield another deposit of orange-colored 

 crystals of cruso-creatinine (E). Gautiee has, further- 

 more, separated three other bases from the mother-liquors 

 of the crystals obtained as above. Thus, a base which he 

 named pseudoxanthine is stated to have been obtained by 

 evaporating the alcoholic mother-liquors of B, D, E (?) in 

 a vacuum, taking up the residue with water, and precipi- 

 tating the hot solution with copper acetate. The precipitate 

 is decomposed with hydrogen sulphide, and the aqueous 

 solution, filtered while boiling-hot, yields a deposit of a 

 sulphur-yell o^v powder of pseudoxanthine. Thus, by tJie 

 use of alcohol, ether, and water, Gactier, at-cording to his 

 statement, has succeeded in obtaining a sharp separation 



