INFLUENCE OF MUSCULAR EXERTION UPON METABOLISM: 195 
both during fasting and with a daily ration of 1500 grams of lean 
meat. The results obtained were as follows: 
Number of Meat Water Urine Urea 
Experiment. Gas ae | Gees | ae 
I 0 Rest 258 186 14.3 
eee eee eee eee ree eases Work 872 518 16 ‘ 6 
Rest 123 145 11.9 
DS paiaratvaho abate: 0 Work 527 186 12.3 
Rest 125 143 10.9 
Rest 182 1060 109.8 
DLT ccpuncanieinians Sistem ne 1500 Work 657 1330 117.2 
Fert 140 1081 109.9 
or. 412 1164 114.1 
IV ee 1500 | Rest 63 1040 110 ‘ 6 
The average increase of the proteid metabolism, as measured 
by the urea excreted, was in the fasting experiments 11.8 per cent. 
and in the experiments with food 4.95 per cent. The absolute 
difference in grams, however, was materially less in the fasting 
experiments, although approximately the same amount of work 
was performed in both cases. A similar experiment upon an 
older and quite fat dog while fasting showed an increase of only 
6 per cent. in the proteid metabolism. 
Subsequently Pettenkofer & Voit * made similar experiments 
upon a man, ‘the work consisting in turning a heavy wheel provided 
with a brake. The work was performed in the respiration appara- 
tus. The results showed a large increase in the carbon dioxide 
excreted, but scarcely any effect was noted upon the excretion of 
nitrogen, as will be seen from the following table: 
Water Excreted. 
i Carbon |____________| 9 Number 
of Unie, Mercia Tn Evapo- Taken Up. Hine: 
Sr Grms. || Urine, rated, Saris: ments, 
Grms. Grms. 
Fasting 
Rest ........-. 12.4 716 1006 821 762 2 
Work ......... 12.3 1187 746 1777 1072 1 
Average diet : 
Rest cate togeotecesare 17.0 928 1218 931 832 3 
Work .........- 17.3 1209 1155 1727 981 2 
* Zeit. f. Biol., 2, 478. 
