106 



2. Considerable haemolysis and decrease of the number of 



erythrocytes. Super-production of bile. Transmission of 

 bile pigments into tlie blood, icterus. 



3. Strong haemolysis (when more tlian jV of the haemoglobin of 



the body is dissolved in the j)lasma) elimination of haemo- 

 globin through the kidneys : Red uruie. 

 Deaths very frequent. 



4. Enormous haemolysis, kidneys strongly affected ; red blood 



cells in the urine ; haematuria, oliguria, anuria. i(,raeniia, 

 e.rihis lethalis. 



Examples.* 



Mule 356. — Injected on the 13tli November, 1903, with a mixture of 

 different sera. 



14/11/03, number of blood corpuscles, 6,100,000. 

 15/11/03, „ .. 2,640,000 Red Urine. 



16/11/03, ., .. 2,560,000 



17/11/03, „ „ 3,366,000 



18/11/03, „ ., 4,560,000 



19/11/03, „ .. 4,860,000 



20/11/03, „ „ 4,246,000 



21/11/03, „ „ 4,100,000 



Mule 356 died on the 21st November, 1903. This animal suddenly 

 showed an alarming dysi^noe, accompanied by a whistling and 

 trumi^eting sound. It died within an hour after these symptons had 

 started. 



Horse 348. — Injected on the 20th Noveml)er, 1903, with a mixture of 

 different sera. The count of red blood corpuscles was as follows : — 

 19/11/03, blood count, 6,020,000 per m.m. 

 20/11/03, ., 6,332,000 



21/11/03, .. 4,706,000 



22/11/03, „ 3,820,000 



There was a distinct jaundiced condition of the mucous membrane 

 of the eyes, on which several blood spots were also noticed. Red urine 

 was voided. 



23/11/03, blood count, 3,006,000 per m.m. 

 24/11/03, „ 3,506,000 



25/11/03, ., 3,966,000 



26/11/03, ,. 3,392,000 



27/11/03, „ 4,632,000 



Urine was again clear ; Esbach's albumen test gave a strong pre- 

 cipitation. 



28/11/03, blood count, 4,126,000 

 29/11/03, .. 4,612,000 



Albumen was less in the urine than on 27/11/03. 

 30/11/03, blood count, 5,552,000 

 1/12/03, „ 4,320,000 



* Copied from Ann. Eep. Govt. Vet. Bact., 1903-04, 



