Notes on the Pathological Anatomy o( Pleuro- 

 pneumonia Contagiosa Bovum. 



By Dr. K. F. Meyer. 



No attention has been paid to the lesions caused by the virus of 

 pleuro-pneumonia in the lungs and in the tissues generally, since the 

 classical investigations of Sussdorf,* Pourcelot,"|' M'Fadyean,J and 

 Csokor.§ This is all the more astonishing, for since the discovery of 

 Nocard of the micro-organism of pleuro-pneumonia (which was made 

 since the publication of the papers cited above) we are now able to verify 

 the histological lesions with the aid of pure cultures. 



It is difficult to assign any -reason why such investigations have not been 

 carried out. It may be that, thanks to energetic prophylactic measures, 

 this once so fatal disease has received such a check that suitable material 

 for investigation has become unobtainable; or else, that in consequence 

 of the mutual interdependence of modern research, which all seems to 

 tend in the same direction, workers have left this problem to take up 

 more sensational ones, which might be described as the fashion of the 

 day. I am, however, of the opinion, that it will be amply rewarded if 

 we take up the study of old, well established phenomena from the modern 

 points of view, especially considering the results and technique elaborated 

 by V. Prowazek|| and Lipschutz^ for visible filterable micro-organisms. 



From the observation of various changes which are absolutely specific 

 for this disease, one is forced to draw conclusions as to the effect af the 

 noxes of the infection. These changes will accordingly be employable in 

 diagnosing the disease. 



The macroscopic lesions in the lungs in pleuro-pneumonia (exudative 

 fibrinous pneumonia and pleuritis) cannot be used to diagnose the disease, 

 as they can appear primarily or secondarily as lesions due to other 

 diseases ; the various histological changes on the other hand are quite 

 specific. This can be seen to a hmited extent from the already existing 

 literature on this subject. It is very useful to be able to make a diagnosis 

 of the disease entirely from the histological lesions, without having to 

 wait for the result of cultures, especially here, where pleuro-puenmonia 

 is of fairly frequent occurrence. 



*Deutsche Ztsohrift f. Tiermedizin, 187!), V. Bd., page 3r>S. 



flAon Medical, ISSl, page U">. 



JThe Journal of Comiiarative Pathology, -l/Kl/lHDl, page 338. 



§Wiener Kliiiische Wochenschrift, 1H94, page 064, and Lehvbiich der Gerichtlichea Tierheilkunde 2. 



Haifte, Wieii 1891, page 4h-,. 

 II Arbeitenaus dem Kaiserlich, Gesumlheitsamt 1!)05-Ufi, Munch. Meiliz. Wochenschrift, lOOS. 

 4 Centralblatt f. liacteriolugie, Btl. XLVIII, 11)II8, Heft 1, page 79. 



