lofi 



It is now evident that the diseased process (phlegmon) which arises 

 under the influence of pleuro-pneumonia virus is absolutely specific. 

 Regeneration, which takes place so readily in other diseases of the muscles, 

 does not happen here, for all the phenomena following the myositis tend 

 towards cicatrisation. Interruption of circulation is here the cause of 

 all changes, and the tangled plexus of blood vessels represent nothing 

 else than collateralia seeking in vain (as far as can be seen on my sections) 

 for a connection. 



Microscopic Lesions of the Lymph-Glands. 



The most prominent lesions in the lymph glands mentioned in cases 

 1, 3, and 6 were in the capsule and the sinus, they compliment the observa- 

 tions made in the other organs in the most remarkable manner. 



The capsules measure 4-6 to 6-1 mm. ; their structure is fibrous and 

 stratified, and yet contains but few connective elements. The vasa 

 afferentia which normally increase in size in the capsule are enormously 

 enlarged, and their ramifications nearly fill the whole tissue ; the cavities 

 thus formed contain fibrine and thick deposits of leucocytes on their walls. 

 The arteries which branch in the capsule are distended with erythrocytes 

 and surrounded with the small cellular deposit usual in pleuro-pneumonia. 

 The lesions would have been absolutely similar to those in the lungs and 

 the muscles had it not been that they were complicated by the sero- and 

 leucocytotactic inter-action of stratified thrombus on the hylus causing 

 a large deposit of pigment in the form of haemosyderin crystals, and had 

 it not been for the very small quantity of connective elements formed. 

 In the tissue of the glands the sinus of the cortex are remarkable ; these 

 are filled with granulated albuminous matter, provided irritation is not 

 caused by the proximity of an inflammatory process ; if this is however 

 the case they form bands or domes of round cells around the lymph follicles. 

 The medulla becomes looser towards the centre of the gland and abnor- 

 malities become rarer at the same time. If a few of the blood vessels in 

 the trabeculae were not thrombosised, the lesions would be those of acute 

 lymphadenitis. 



In consequence of these conditions we find changes around the blood 

 vessels as usual in pleuro-pneumonia. The changes taking place in the 

 lymph vessels are dependent on the conditions surrounding them ; the 

 vessels in the capsule and those immediately below and above it are the 

 first to suffer. The typical incrustations around the blood vessels are not 

 wanting. 



The Microscopical Lesions of the Capsules op the Articulations 



AND OF THE SyNOVIALIS. 



Macroscopic lesions were present in the joints described, although 

 no suggestion was made as to their origin. Infection fer continuitatem 

 is out of the question, except in one case in which it occurred in the 

 articulatio scapulo-humeraUs ; it must be supposed to take place by 



