Fowl Cholera, Fowl Typhoid and Fowl Plagvs 109 



dying it is best to market all flocks in which the cholera 

 appeared. This latter precaution will often prevent a second 

 outbreak some months later. 



Methods of prevention are always the most satisfactory. 

 The careful poultryman will guard his flock against all in- 

 fectious diseases by methods of quarantine, disinfection and 

 general cleanliness. At the same time the birds should be 

 fed to keep them in the best of health. On these points read 

 Chapter II. 



A large amount of work has been done upon remedies and 

 preventives for this disease. Recently Hadley^ has rec- 

 ommended the subcutaneous injections of 5 per cent car- 

 bolic acid as a treatment for individual birds. This author 

 says: "At the Rhode Island Station attempts have been 

 made to prevent the development in fowls of cholera artifi- 

 cially produced by inoculation with the fowl cholera or- 

 ganism. The protective inoculations have involved sub- 

 cutaneous inoculations with a 5 per cent solution of carbolic 

 acid in amounts of from 2 to 4 c.c. daily. 



"The results thus far secured show that the inoculations 

 as given protected artificially infected birds, and did no harm 

 to birds that were in normal health. They therefore suggest 

 that subcutaneous inoculations with carbolic acid have a 

 protective and perhaps a therapeutic value in fowl chol- 

 era." 



Much work has also been done, especially in Europe, upon 

 methods of protective inoculation against this disease. The 

 best success has been obtained by the use of immune sera. 

 Such a serum is prepared by immunizing a large animal, 

 horse or cow, by repeated injections of this organism. The 

 serum from this animal is then collected and used to inoculate 

 healthy birds. Such an immune serum gives a passive im- 



' Hadley, P. B., "Fowl Cholera and Methods for Combating It." 

 Rhode Island Agr. Expt. Stat. Bui. 144, pp. 309-337, 1910. 



