30 BACTERIOLOGY 



course of this work that the Abbe system of substage con- 

 densing apparatus was first used in bacteriology; that the 

 aniline dyes suggested by Weigert were brought into general 

 use; that the isolation and cultivation of bacteria in pure 

 culture on solid media were shown to be possible; and that 

 animals were employed as a means of obtaining from mix- 

 tures pure cultures of pathogenic bacteria. 



With the bounteous harvest of original and important 

 suggestions that was reaped from Koch's classical series 

 of investigations bacteriology reached an epoch in its develop- 

 ment, and at this period modern bacteriology may justly 

 be said to have had its birth. 



Note. — I have presented only the most prominent inves- 

 tigations that will serve to indicate the lines along which 

 the subject has developed. For a more detailed account 

 of the historical development of the work the reader is 

 referred to Loffler's instructive and entertaining Vorlesungen 

 iiber die gescMchtliche Entwickelung der Lehre von den Bac- 

 terien, upon which I have drawn freely in preparing the 

 foregoing sketch. 



