LESS COMMON PYOGENIC ORGANISMS 345 



the infections caused by the members of group A, while it 

 may be inactive upon those caused by the members of 

 group B or C. 



The method adopted by Cole in his work upon the treat- 

 ment of pneumonia with antipneumococcus serum (to be 

 described later) is essentially along this line and his results 

 thus far point directly to the logic of the procedure. 



Note. — If the opportunity presents, obtain cultures from 

 a case of erysipelas. Compare the organism thus obtained 

 with streptococcus pyogenes. Inoculate rabbits both sub- 

 cutaneously and intravenously with about 0.2 c.c. of pure 

 cultures of these organisms in bouillon. Do the results 

 correspond, and do they in any way suggest the results 

 obtained with micrococcus aureus when introduced into 

 animals in the same way? Do these streptococci flourish 

 readily on ordinary media? 



THE LESS COMMON PYOGENIC ORGANISMS. 



The organisms that have just been described are com- 

 monly known as the "pyogenic cocci" of Ogston, Rosenbach, 

 and Passet, and up to as late as 1885 were believed to be the 

 specific factors concerned in the production of suppurative 

 inflammations. Since that time, however, there has been 

 considerable modification of this view, and while they are 

 still known to be the most common causes of suppuration, 

 they are also known to be not the only causes of this process. 



With the more general application of bacteriological 

 methods to the study of the manifold conditions coming 

 under the eye of the physician, the surgeon, and the patholo- 

 gist, observations are constantly being made that do not 



