90 YETEEINAEY TOXICOLOGY 



anaemia, weakness, and eczematous eruptions, results from 

 prolonged administration of bromides. 



Like the bromides, large doses of iodides cause enfeeble- 

 ment of the heart and cerebral and spinal depression, pro- 

 longed exhibition causes iodism, and large doses are fatal 

 to dogs, which show depression and gastric irritation due 

 to salt administration (Pinlay Dun). But large doses of 

 iodide are given to horses and cattle. Thus, in actino- 

 mycosis of cattle 2 drachms twice daily cause no toxic 

 effects even after prolonged treatment, and in obstinate 

 cases 2 drachms potassium iodide with 5 grains mercury 

 biniodide twice daily for several weeks are used (Wallis 

 Hoare). 



Iodoform, so valuable as an antiseptic dressing, is rarely 

 given internally. Not being easily absorbed from the skin, 

 it does not often give rise to poisoning ; but this may happen 

 with dogs through licking. In dogs and cats it causes 

 gastric irritation, vomiting, muscular spasms, a lowered 

 temperature, enfeebled heart action, and narcosis. There 

 is albuminuria, and in chronic poisoning emaciation and 

 fatty degeneration of muscles and glands. According to 

 Frohner, dogs are killed by 15 grains per 2 pounds body 

 weight by the mouth, by 20 to 30 grains subcutaneously, or 

 7 grains injected into a serous cavity. An old cow died in 

 thirty- six hours with spasms and narcosis after an ounce 

 and a half (Pinlay Dun). 



In any case of poisoning by iodoform no difficulty ought 

 to be experienced in diagnosis, because the drug will be 

 known to have been accessible, the odour is characteristic; 

 and the symptoms are in accordance. 



CARBON MONOXIDE. 



Oeeuprence. — Carbon monoxide, or carbonic oxide, is to be 

 clearly distinguished from carbon dioxide, or carbonic acid. 

 It is inflammable and chemically neutral. Carbon mon- 

 oxide is formed in the incomplete combustion of carbon, 



