OEGANIC POISONS AND DEUGS 105 



The chief symptoms are — Sneezing and coughing and 

 increased salivation ; temperature subnormal ; staggering 

 gait, commencing with loss of motor power of hind quarters ; 

 great prostration and death from heart failure. 



Izal is less dangerous than creolin, but may poison, 

 Showing similar symptoms. Applications of it to the skin 

 ought not to exceed 10 to 15 minims per pound body weight 

 of dogs or cats. 



According to Dollar ,^° who investigated the clinical value 

 of ' Jeyes ' and creolin, these agents are safe as ordinarily 

 used with the horse. With the dog his observations on the 

 whole agree with Hobday's, and he advises 10 to 15 minims 

 of creolin per pound live-weight as the upper limit for fine- 

 skinned, delicate, and in-and-in bred dogs, such as toy 

 varieties, although as large a proportion as 40 minims may 

 be safe for adults and mongrels. He found that a cat of 

 7 pounds weight, three years old, after well rubbing with 

 5 drachms of 'Jeyes ' in 5 per cent, solution was poisoned, 

 and died within fourteen hours. But he forcibly argues 

 that this preparation is no worse than any lotion or any 

 other efficacious agent. 



Post -Mortem Appearances. — Following internal ad- 

 ministration there is observed intense irritation of the 

 gastro-intestinal mucous membranes ; that of the rumen 

 may become detached, but this is a frequent post-mortem 

 observation of no special significance. Frequently there 

 is a strong smell of carbolic acid in the viscera ; the 

 pharynx and oesophagus exhibit pallor. 



In creolin poisoning, one notes the smell of the agent ; 

 the heart cavities contain dark blood clots, and the small 

 vessels, particularly of the brain, are congested. 



As characteristic of chinosol are the smell and colour of 

 the agent, and the presence of frothy saliva in the pharynx, 

 oesophagus, and stomach. 



Treatment. — Carbolic acid after absorption is eliminated 

 in the form of sulphuric acid derivatives or sulphocarbo- 

 lates in the urine. These compounds are comparatively 

 harmless, and in using sodium sulphate as an antidote it 



