CHANGES IN THE NON-PREGNANT UTERUS 109 



from the edges of the adjoining epitheUmn which had not 

 suffered destruction. In this way the re-formation of the 

 epithehum is sufficiently accounted for, since, as aheady re- 

 marked, only a very inconsiderable number of cells is removed 

 during the sheep's prooestrum. 



Congestion of the stroma gradually diminishes, and the 



pig. 









S-^ 



Fl0. IS.^Section throngh portion of uterine mucosa of sheep showing 

 black pigment (pig.) formed from extravasated blood. 



mucosa as a whole undergoes a shght shrinkage. It would 

 appear that a few new capillaries are formed, but there is no 

 evidence that any of the extravasated corpuscles are gathered 

 up afresh into the circulatory system. On the other hand, 

 there are ample indications that all those corpuscles which 

 remain in the tissue become transformed into pigment, as 

 originally concluded by Bonnet.^ According to this investigator, 

 the extravasation takes place in the deeper mucosa, and the 



' Bonnet, " Ueber Melanose der Uterinschleimhaut," &c., Deutche Zeitseli. 

 f. Thicrmedizin, vol. v., 1880, and vol. vii., 1882. " Beitrage zum Embryologie 

 der Wiederkauer," &c., Arch. f. Anat. a. Phys., Anat, Abth., 1884. 



