ORGANS OF INTERNAL SECRETION 



319 



Grigoriefi/ Ribbert,^ and Rubinstein ^ carried out experi- 

 ments upon rabbits which confirmed those of Knauer, the 

 ovaries being transplanted in various abnormal positions. 

 Grigorieii also records two cases in which ovaries were success- 

 fully transplanted from one individual to another (heteroplastic 

 transplantation). Ribbert found, in his experiments, that 



Fig. 68. — Transyerse section through bitch's uterus 9| months after 

 ovariotomy. (From Blair Bell, British Medical Journal and Trans. 

 Royal Society of Medicine.) 



during the first month after transplantation the peripheral part 

 of the grafted ovary remained unaltered, but the central part 

 became transformed into connective tissue. At a later period, 

 however, the central portion was again found to contain follicles. 

 This fact is attributed to the conditions of increased nutrition 

 which Ribbert supposed to prevail when the ovaries had been 



^ Grigorieff, " Die Schwangerschaft bei Transplantation der Eierstocke," 

 Central, f. Gynak., vol. xxi., 1897. 



* Ribbert, " Uber Transplantation von Ovarien, Hodeo, und Mamma," 

 Arch. f. Entwick.-Mechanik, vol. vil., 1898. 



'Rubinstein, "Extirpation beiden Ovarien," St. Petersburg Mediz. 

 Wochenschr., 1899. 



