458 STUDIES IN GENERAL PHYSIOLOGY 
TABLE II 
(V=110) 
I | II | Average 
FINO, we cacicucs 9.2% 8.8¢ 9.0% 
AGM ieiisin cow citer s 9.5 8.6 9.0 
ie FE Oe 9 ayes 8.0 9.3 8.6 
When V=110, », is about 875 for HCl instead of 377. 
The degree of dissociation is therefore only slightly different 
from that when V=210. Nevertheless, the effect of the 
acid is not doubled when the concentration is doubled, but 
only increased about 50 per cent. Pronounced toxic effects 
already show themselves when V=100. I need not again 
point out how well the values agree with each other. 
I wish finally to give a series of experiments with 
KHSO, andNaHSO,. One-tenth normal solutions of these 
acids were used of which 10 ¢.c. were added to 100 c.c. of 
a 0.7 per cent. NaCl solution. The amount of water 
absorbed by the muscle is given in Table III. 
TABLE III 
(V =110) 
| I | II TIT IV | Average 
KAS Oy sschatassaaiary 7.6% 8.2% ee er 7.9% 
NaHSO yee ey adseese 8.1 9.8 7.8% 7.2% 8.2 
The values are quantitatively almost equal to those of the 
other acids, especially sulphuric acid. In these concentrations 
the lesser degree of dissociation of the sulphuric acid when 
compared with nitric or hydrochloric acid is clearly shown. 
If we sum up the results of all these experiments, we can 
say that the acid effects (when V = 100 or 200) of HCl, 
HNO,, {}H,SO,, KHSO,, NaHSO,, so far as these effects 
are expressed in the absorption of water, or, more accurately, 
im the increase in the weight of the muscle, are chiefly ion 
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