194 MICROBES, FERMENTS, AND MOULDS. 
Many other bacteria appear in the intestines when 
the disease is approaching its end, but the bacillus in 
question is the only one found in the blood and 
internal organs, so that it is really characteristic of 
the disease. 
Gaffky, a German micrographist, and a pupil of 
Koch, has succeeded in the artificial culture of this 
microbe, taking it from the spleen of persons who died 
of typhoid fever. It is actively developed on gelatine 
and potatoes, becomes very lively and produces endo- 
FESO Q 
es is 
Fig. 86.—Bacilli of typhoid fever (x 1500 diam.): three red corpuscles may be 
observed in the sume preparation. 
genous spores at a temperature of 38°. But the inocu- 
lation of animals with the disease has hitherto been 
unsuccessful, at least so as to reproduce in them an 
affection of the intestines, really resembling that of 
Peyer’s glands in man. 
The horse is the only animal affected by a similar. 
disease, which has also been called typhcid fever. In 
1881, the horses of the Paris Omnibus Company were 
decimated by an epidemic of this nature. But the 
lesion of Peyer’s glands cannot be compared with that 
which occurs in the same glands in man, and no 
special microbe has yet been discovered. 
