68 CANINE DISTEMPER 
distemper. The young hounds were also inoculated 
(half dose), and so far no deaths from distemper have 
been reported. The Duke hopes he may be equally 
successful this year.” 
An extract from a further letter from Mr. T. Newman, 
huntsman to His Grace the Duke of Beaufort, reads: 
“As soon as the hounds were brought in from ‘ walk,’ 
they were isolated, fasted for about twelve hours, and 
given a gentle dose of castor-oil, and then temperatures 
taken, to make certain they were in a fit state to inocu- © 
late. Then they received 7 c.c. of vaccine. Took their 
temperatures for three days to make sure of the reaction, 
which in most cases sent their temperatures up from 
102° F. to as high as 104° F.; kept them still in isolation 
for a period of ten days from the first inoculation, then 
did them again with to cc., taking their temperatures 
for three days. I find that in the majority of cases it 
reacts the second time. Then I put them together. Out 
of the 23} couples that were inoculated, only about one 
couple have shown any signs of distemper, and then 
only ina mild form. If we go on with the same results 
as this year, it will be the greatest boon that has ever 
been brought out.” 
Further testimony as to the value of Copeman’s 
vaccine was also given by Karl Hopf, the well-known 
St. Bernard breeder, in a letter to The Dog World ; but 
it is phrased in similar terms to the other letters, and 
on that account, perhaps, need not be recapitulated. 
M‘Gowan, on the other hand, obtained no definitely 
good results with the use of prophylactic vaccines, 
though he considers they may prevent toxic phenomena. 
Ferry’s Polyvalent Polymicrobial Vaccine-—The very 7 
latest production is the vaccine introduced by Ferry— 
an American veterinary surgeon, who, as I have fully 
described under “ Etiology,” discovered B. bronchisepticus, 
