70 CANINE DISTEMPER 
results. All of these dogs are exposed to infection before 
being brought to the laboratory, and many of them have 
already contracted the disease, so that the fact that we 
are able to save so many speaks well for the value of the 
inoculations.” 
The experiments on the wild animals were said to be very favourable, 
and apparently corroborated the work previously carried on with dogs 
from the dog pound. Ferry was surprised to learn that the vaccine 
seemed to produce marked beneficial results in other animals, and the 
striking results convinced him that the B. bronchisepticus would probably 
be found in other species of animals. 
The bacterin is now issued in two forms: (1) As a sus- 
pension of the killed organisms in normal saline solution, 
and (2) in a dry state as hypodermic tablets. 
Composition of Ferry’s Vaccine.—It is prepared not only 
from several strains of B. bronchisepticus (6 parts), but 
with an admixture of those other organisms which are so 
constantly found complicating the primary infection— 
namely, Staphylococcus pyogenes albus (1 part), St. py. aureus 
(1 part) and Streptococcus pyogenes (2 parts). 
The suspensions of the dead organisms are diluted to 
a standard strength, and these so combined that the 
resulting mixture contains the desired number of organ- 
isms per cubic centimetre—namely, 1,000 million. The 
product is preserved with o:2 per cent. cresol. In the 
preparation of the tablets, the bacterial suspensions are 
dried, and the organisms then combined with a suitable 
tablet base, so that each tablet will contain 500 millions. 
Therapeutic Indications.—This bacterin* is indicated as 
a prophylactic and curative agent in all forms or types of 
canine distemper and sequela. Preventive treatment 
* Wherever the term “bacterin” is employed, it needs to be carefully 
borne in mind that a distinction was made between a vaccine and a 
bacterin by the United States Bureau of Animal Industry, which laid 
down the ruling that in veterinary medicine all preparations which con- 
tain living organisms, whether attenuated or not, shall be termed 
“vaccines,” and all suspensions of dead organisms shall be denominated 
