PREVENTIVE INOCULATION 13 
the reaction is very severe, however, it may be well not 
to increase the size of the dose, but to continue the last 
or even a lesser dose until only a moderate reaction 
is produced, when the ascending scale may be again 
resorted to. 
Evidence upon the Efficacy or Otherwise of Ferry’s Bacterin. 
—In addition to the observations of Ferry, Torrey, and 
Rahe quoted above, several veterinary practitioners have 
written expressing their appreciation of this vaccine and 
the encouraging results obtained with it. Mr. Stans- 
field, of Rawtenstall, the well-known breeder of collies, 
writes: “I have not had a single case of distemper in 
my kennels during 1915 and 1916. Several puppies 
I inoculated with your vaccine have been frequently 
exhibited, including ‘Laund Laureate,’ who won the 
Challenge Certificate at the Richmond Show, and up 
to now have proved immune to distemper.” 
My own experiences, however, have been variable, and 
on the whole fairly successful. Out of seven dogs which 
I inoculated with Ferry’s bacterin at different periods, 
not as an experiment, but to satisfy the desires of clients 
and friends, the results were as follows : 
Case 1.—Collie puppy, 24 months old. Gave three 
inoculations at the usual prescribed intervals, and ob- 
tained slight reactions each time—v.c., malaise, inappe- 
tence, rise of temperature to 103° F. Was informed 
about four months later that the dog was sick with dis- 
temper, and after an illness of nearly three weeks it died. 
Case 2.—Collie puppy, 2} months old. Same pro- 
cedure as No.1. Reaction more marked. No history of 
subsequent naturally contracted disease. 
Case 3.—Airedale puppy, 4 months old. Same pro- 
cedure followed as laid down in the directions on pre- 
ceding pages. Good reaction obtained with the first 
dose, but not with the second or third. Dog was 
poorly for about a week, an occasional cough being 
noticed and slight diarrhcea : then became normal, and 
