SYMPTOMS 95 
tions of pus are soon found in the anterior chamber, 
which find exit through the corneal perforation, and the 
aqueous and vitreous humours may escape by the same 
channel. All sight has then vanished; the eyeball 
collapses and shrivels, and there is no alternative but to 
.totally remove what remains by surgical means. In rare 
cases panophthalmia may suddenly appear in the absence 
of any septic infection through a corneal perforation, and 
run an acute rapid destructive course in which all parts 
of the eye are intensely inflamed, and rupture of the 
cornea accomplished from within, with consequent loss 
of the humours. Panophthalmia may be transferred 
from an affected to an unaffected eye by a sympathetic 
process, the condition being known as “sympathetic pan- 
ophthalmitis.” 
Parenchymatous Keratitis.— Not rarely, instead of 
ulcerative processes occurring one finds a parenchyma- 
tous keratitis or bluish milky opacity diffused over the 
whole of the anterior part of the eyeball (which has 
been described by some as having a “ground-glass” 
appearance) and which may subsequently extend in- 
wards and involve the iris, with resulting crits. This 
last condition is marked by pain, congestion in the 
ciliary region, photophobia, contraction of the pupil and 
discoloration of the iris. These diffuse opacities some- 
times remain for the rest of the animal’s life, especially 
in old dogs, and whilst they do not seem absolutely to 
deprive the eye of all sight for near objects, they certainly 
seriously curtail vision for long distances. 
Interstitial keratitis, parenchymatous keratitis, as also 
ulcerative keratitis, may affect one or both eyes, pan- | 
ophthalmia usually only one eye, and ordinary benign 
conjunctivitis practically always both eyes... Opacities— 
like many other pathological conditions—though arising 
sometimes in a few hours, frequently require many 
