176 CANINE DISTEMPER 
in quantities of grs. v. to grs. xv. three times daily ; it is 
a fairly safe drug, very large doses being required to 
set up toxic effects, these being of a paralytic nature. 
However, it is questionable whether antipyresis is 
justifiable when elevation of temperature is only slight 
or of short duration, for, as Miller correctly observed, 
it deprives us of the symptom of temperature, which is 
of the greatest importance during the course of the 
disease, and, moreover, many of the agents used are 
cardiac depressants. 
It is only when pyrexia has been long persistent or 
has attained an alarming height, thus threatening to 
induce some deleterious effect upon the vital organs— 
particularly the heart—that interference becomes of 
paramount importance. 
Antipyrine is a first-rate febrifuge for dogs, producing 
its effect within half an hour, without any untoward 
action, and it may be given in doses ranging between 
ers. v. and ers. xv. frequently during the day. 
Antifebrine is another quick-acting drug of great value 
for rapidly lowering temperature in cases of fever arising 
from pneumonia or any other cause; it is cheap and safe, 
and is usually administered in doses of grs. ii. to grs. x. 
every two or three hours. — 
Both of these agents are quicker in action, more 
certain, and preferable to quinine as antipyretics, and 
deserve to be more widely used in canine practice than 
they have been hitherto. 
Other remedies for fever are the various salines, such 
as magnes. sulph. or Glauber’s salt (a pinch of either of 
which could with advantage be dissolved in the drinking 
water); warm clothing to the body, but cool, fresh air to 
breathe ; rest, and a regular action of the bowels. — 
Apart from these measures, and advice as to isolation 
and segregation of the ailing and in-contact animals, with 
