14 The Farmer's Veterinary Adviser. 



become impregnated with lime- salts (calcified), it may withei 

 up into a liai-d geiatiniform or horny mass, or it may 

 undergo ya^^j^ degeneration. 



Fatty degeneration is the most common form, and con- 

 sists in the excessive deposit of fatty granules, first in the 

 cells which are in excess or badly nourished, and next in 

 the adjacent tissue, the normal elements of which are re- 

 placed by fatty granules. 



Softening is an almost constant result of inflammation. 

 The exudate infiltrates and separates the tissue elements, de- 

 stroying their cohesion ; its liquefaction impairs this still 

 further, and the more or less perfect transformation of the 

 tissue into embryonic tissue entails the loss of its rigidity 

 and power of resistance. Thus the inflamed brain-tissue 

 may become a mere pulp^ and the inflamed bone may be 

 cut with a. knife. 



Ulceration is closely allied to softening. On the surface 

 of a sore there is an excessive exudation of lymph, whicli 

 loosens and disintegrates the layer of lymph that is already 

 in process of development, and also a part of the tissue be- 

 neath. The cells in these parts fail to develop naturally 

 and to build up good tissue ; they become fatty, die, and 

 together with the tissue in which they lie, break down and 

 pass off as a pulpy debris. Thus the sore constantly deep- 

 ens and widens, or at least refuses to contract and heal. 



Gangrene or death of apart is another effect of inflam- 

 mation. It results usually from the cutting off of the blood- 

 supply through the obstruction of the blood-vessels ; by the 

 pressure of excessive exudation in unyielding structures, as 

 in bone, or under the hoof ; by implication of the inner 

 coats of the blood-vessels in the inflammation, when the 

 contained blood will clot and obstruct them ; or by block- 

 ing with the blood-clots that have been formed at a dis- 

 tance and washed on in the blood-current to be arrested 

 when they reach, vessels too small to admit them. Like 



