Bacteriology 



383 



factious and not toxic in character though brought about by filtered 

 fluid. 



The virus resists freezing but is readily destroyed by heating to 

 45°-5o°C. for half an hour. 



Various attempts were made by Kraus and Wernicke,* Lentz 

 and Huntemiillerf and MarksJ to infect rabbits with the virus, but 



_ Fig. 140. — Micro-organism causing epidemic poliomyelitis. 3, Separate glo- 

 boid bodies, X 1000; 4, aggregated masses of globoid bodies, X 1000; 5, chains 

 and pairs of globoid bodies, X 1000; 6, chains of globoid bodies compared with 

 Streptococctis pyogenes, X 1000; 7, agar fragment showing pairs of globoid bodies 

 compared with Streptococcus pyogenes, X 1000 (Flexner and Noguchi, in 

 Journal of Experimental Medicine). 



though some successes were reported, there seerris to be no develop- 

 ment m the rabbit of lesions or disturbances resembling the char- 

 acteristic lesions and symptoms of acute anterior poliomyelitis in 

 man and the monkey. 



+ 1!?^"'^'^'^^ "^^'^- Wochenschrift," 1909, xxxv, 1825; 1910, xxxvr, 693. 

 T ^ Zeitschrift fur Hygiene," 1910, lxvi, 481. 

 I Jour. Exp. Med.," 191 1, XIV, 116. 



