the parasites were exceedingly numerous; Plate I., figs,. 1 and 2, representing the 

 degree of invasion. In the lungs the semi-purulent cysts consisted of leucocytes and 

 disintegrating cellular tissues; a few Sarcospores in process of decay were seen. It 

 is extremely probable, but not proved, that these inflammatory areas in the lungs 

 resulted from the presence and disintegration of Sarcocysts. In the spleen, liver and 

 kidneys, a very few degenerating spores were seen and much granular pigment 

 matter. 



The myocardium contained very numerous parasites. While, as already stated, 

 all of the skeletal muscles were extensively invaded, those of the head, poll and extre- 

 mities were, if anything, the more heavily infested. 



Case III. — (Animal No. 83) Steer, 3 years old. Similar condition to preceding 

 cases, but the disease not so far advanced. During the past three months, in which 

 the animal had been hand-fed and well cared for,»the symptoms have increased in 

 severity. Depression is deepening, muscular action stiff and slow. Jaws swollen. 

 The animal was cast and a small fragment of muscular tissue excised from the tongue, 

 Flexor Metacarpi Externus, the masseter, and one the cervical muscles. Sarcospores 

 were found in preparations of each,' not as numerous as in cases I. and II., but still 

 farily plentiful. The present condition of the animal leaves little chance for recovery. 



Cases IV., V. .and VI.— (Animals 84, 85 and 86). Steer and two heifers, two, 

 three and two years old respectively. The condition is approximately the same in each, 

 namely, slow, sluggish muscular action, depression, and a dejected, unthrifty appear- 

 ance. These animals were cast and operated on as in Case III. The muscles examined, 

 and the results as follows: — 



Case IV. — Masseter — Sarcosporidiae numerous. 



Upper cervical — Sarcosporidiae fairly numerous. 

 Tongue — Sarcosporidiae fairly numerous. 



Case V. — Flexor metacarpi externus — Sarcosporidiae not found. 

 Middle cervical — Sarcosporidiae fairly numerous. 

 Tongue — Sarcosporidiae very numerous. 



Case VI. — Lower cervical — -Sarcosporidiae numerous. 

 Tongue — Sarcosporidiae numerous. 



Thus in all muscles examined, with the single exception of a very small frag- 

 ment of the flexor metacarpi, Sarcosporidiae were present. 



(b) In the Equines Suspected of Loco-poisoning. 



Case VII. — (Animal No. 91.) Gelding, rising 3 years old showing symptoms of 

 loco-poisoning as a yearling.' — (Dr. Hilton.) 



The condition, briefly, on admittance to the quarantine station, October 27, 1907, 

 depression, restlessness ; slowly wandering about without aim or object. Slow, high, 

 hesitating gait, as if walking over obstacles. When undisturbed, the head is carried 

 very low, down to the level of the knees, the neck often twisted. When suddenly 

 startled, there is a brief period of excitement and the animal may stagger and fall. 

 At present date, after a period of five months, the condition has become greatly 

 aggravated, and it does not look possible for the animal to live much longer. Flexion 

 and extension of the limbs are extreme, and brought about very slowly, and it is 

 quite impossible for the animal to run, trot or move out of a slow walk. The bones 

 of the face appear much swollen, and the expression truly melancholic and pitiable. 

 Small sections of the tongue and masseter muscle were removed and Sarcocysts were 

 found in micro-sections of each. The parasites were few in number, and small, 

 though containing spores, 



