ALCOHOL, DISEASE, AND HEREDITARY DEFECTS 273 
the very decided preponderance of sterile matings and stillborn 
or short-lived young in the experiments with the alcoholized 
animals. And the results are all the more convincing because 
the alcoholized animals had been previously bred and proven 
capable of bearing normal offspring. 
The following table gives a summary of results up to 1916: 
Effects of Alcohol on the Descendants of Treated Animals 
Neg. Result No. of Young dying 
Condition of the animals |No- of} or early |Stitborn| srintorn|Living| soon after |Tolal| Surviving 
matings! abortion | tillers young Litters birth dead| young 
Alc. @ % norm. @........ 90 37 10 20 43 35 55 47 
Norm. O 2 le ccscc cus 33 7 4 12 22 23 35 21 
Ale oF m ales D 3 suc cons « 4 20 4 8 7 12 20 14 
Stitamery ss: ses asee ee 2 164 64 18 40 82 70 110 82 
Control norm. o’x norm. .} 90 22 2 8 66 19 27 99 
G treated during pregnacy 4 ° ° ro) 4 I I 7 
and gener. x norm......... 46 10 3 8 33 29 37 25 
gnd.-genér:% alee wus sae vee 53 16 8 17 29 22 39 28 
and gener. x 2nd gener.... . 95 29 7 16 59 43 59 52 
3rd gener. x 3rd gener...... 48 20 7 14 2 19 33 13 
3rd gener. x 2nd gener..... 33 15 4 8 14 16 24 7 
3rd gener. x norm......... 17 3 4 8 10 5 13 7 
grd gener: #.ale: 6. asic seas 3 I ° ° 2 2 2 I 
and, 3rd gener. x 2nd, 3rd 
BENET sis dose wee ae eas 18 9 2 6 A 6 12 4 
More recently additional data were obtained in part from 
animals of unrelated stock, but the results only confirmed the 
previous findings. Some of the general comparisons are shown 
in the following table: 
Progeny of Normal and Alcoholic Guinea Pigs 
Normal Lines|Alc. Lines|Normal Inhert.|Alc. Inhert. 
Total number............... 233 594 41 302 
Lived over 3 months......... 181 383 32 184 
Aborted, premature, stillborn. 27 138 6 17 
Died within 3 months........ 25 73 3 41 
Total died os 2.s4.sdsusismons ied de 52 211 9 118 
Defectives. cic sscsswecevcs ° 15 ° 10 
Undersized. .......22.050055 I 8 I II 
