238 Veterinary Medicine. 



and extend from below upward, and the first nodules may be on 

 the fetlock or hock. 



Symptoms of Chronic Nasal Glanders in Solipeds. The chronic 

 form of the disease follows an indolent course, and local symp- 

 toms are often so slight or equivocal that the true nature of the 

 malady is unsuspected. If the patient is well fed and cared for 

 and not overworked, the malady may run a course of three, five 

 or seven years, and the victim may pass through many hands 

 leaving infection in every stable it occupies. Diagno.stic symp- 

 toms, more or less clear, may be obtained from the discharge, 

 the lesions of the mucosa and the submaxillary glands. 



The nasal discharge may be bilateral, but if confined to one 

 nostril is strongly suggestive of glanders. It may be profuse or 

 scanty, continuous or intermittent, of a yellowish, purulent tint, 

 or greenish, or grayish and with a special tendency to viscidity. 

 In some indolent cases the nostrils may be clean but if there is 

 any matting of the long hairs, or adhesion of the alse nasi, the 

 case is specially suspicious. If it is sanious, flocculent, or bloody 

 it is all the more characteristic, and suggests the supervention of 

 an acute attack. 



The lesions of the pituitary m-embrane are varied. Hypersemia 

 of a purple or violet color is common, especially along the septum, 

 and the mucosa is liable to be somewhat tumid or cedematous. 

 Nodules the size of a pin's head, a pea or larger appear inside 

 the inner ala, or on the septum or turbinated bones, and at first 

 red from extravasation and, as it were vesicular, become grayish, 

 whitish or yellow with points of red and surrounded by a deeply 

 congested areola. Larger nodules forming in the submucosa ap- 

 proach the surface and stand out the size of the tip of the finger 

 and with the same general charactei* as the smaller. Sooner or 

 later these degenerate and form ulcers which bear a resemblance 

 to those of acute glanders but are less angry, and when small and 

 solitary may be taken for simple erosions. In other cases they 

 become thickened and indurated with sharply defined projecting 

 margins, and a yellowish base with points or lines of red. The 

 presence of red, black, green, or brown crusts may also be noted. 



Another lesion frequently observed in indolent cases is a cica- 

 tricial white spot or patch in which the hyperplasia has become 

 partially developed into tissue and shows no tendency to ulcerate. 



