482 Veterinary Medicine. 



mesenteric tubercles point so directly to infection through the 

 food. If it is held that the tubercle bacilli in the milk are harm- 

 less, we wait for evidence of the real cause of such encrease and 

 localizatioji. 



The experiments of Adami show that tubercle is directly trans- 

 missible from man to ox though usually with decreased virulence. 

 More recently, Ravenel using the bacillus derived from the mesen- 

 teric glands of a child, injected intravenously two tuberculin- 

 tested calves, with 5 cc. each of the culture producing exalted 

 hyperthermia, miliary tuberculosis of the lungs, tuberculosis and 

 caseation of the bronchial and mediastinal glands, and death in 

 17 days. Dr. Garnault's experiment on himself, now in prog- 

 ress, has already shown the great danger to a susceptible man, of 

 the bovine bacillus. 



As showing accommodation to environment, Battaillon and 

 Ferre found that the bacillus (mammalian and avian) grown in 

 frogs, Dubard that grown in fishes, Krahl that grown in frogs, 

 snakes, fishes and lizards, and Miieller that grown in the glow 

 worm, thereafter grew at summer temperature (68° F.) and grew 

 poorly or not at all in the bodies of mammalia. 



The tubercle bacillus is primarily and essentially one, but this 

 must not close our eyes to the fact that in different ho.sts and 

 environments it takes on very different habits, so that for the 

 time and in these surroundings, it is materially modified in its 

 pathogenic attitude toward different races. Yet its ready vari- 

 ability when conditions are favorable to change, renders it desir- 

 able to destroy it in all its forms, and especially in those which 

 approximate most closely to those that prey on man and animals. 



An impartial review of the whole field warrants the conclusion 

 that the nineteen young (and therefore comparatively unsuscep- 

 tible) cattle whicli in Koch's hands failed to develop generalized 

 tuberculosis after inoculation with the virulent .sputum of man, 

 and the smaller numbers that resulted in the same way under 

 similar treatment in the hands of Th. Smith, Dinwiddle and 

 Adami, while showing a very marked limitation in the su.scepti- 

 bility of the sound bovine system to weak bacilli from man, can- 

 not disprove the many well authenticated cases of the transmis- 

 .sion of tuberculosis from cow to man and the reverse. The 

 greater potency of the bovine bacillus over that of man, in its 



