Cattle Plague. 631 



liquid and yellowish, grayish or reddish and foetid. Micro- 

 scopically the distension of the glands, (of duodenum, Lieber- 

 kuhn and Peyer), the proliferation and softening of the epithe- 

 lium, the enlargement of the nuclei of these and of the cells of 

 the submucosa, and the profusion of microorganisms are marked 

 features. 



In the caecum and colon the Ie.sions are usually less prominent, 

 though swelling, softening and desquamation of the epithelium 

 often exists, and points and patches of congestion, ecchymosis, 

 and necrosis are not uncommon, particularly in the caecum, and 

 may extend to the muscular layer. 



The terminal portion of the rectum is especially liable to 

 marked congestion and blood extravasation, with more or less 

 desquamation and erosion. The summits of the mucous folds are 

 often of a dark red (port wine) hue, and as this is everted and 

 exposed in defecation or later by the relaxation of the sphincter 

 it becomes a marked lesion even in life. 



The spleen is normal in strong contrast with anthrax in which 

 similar gross lesions are often found on the mucosae and especially 

 the rectum. 



The liver is usually rather pale and soft, as in other cases of 

 high fever and centres of necrosis may be present. The gall 

 bladder contains a variable amount of thin bile. The pancreas is 

 nearly or quite normal. The lymph glands generally and especi- 

 ally those of the mesentery and abomasum are congested, enlarged 

 and softened. 



The kidneys are congested, often petechiated, swollen and 

 softened, with centres of necrosis. The bladder, vagina and 

 uterus .show mucous congestion, and thickening uniformly or in 

 spots with muco-purulent secretion. 



The lungs show spots of hyperaemia, extravasation and at times 

 hepatization, but a ver}' characteri.stic lesion is the interlobular 

 emphysema already referred to as connected with the abdominal 

 pain and the sudden arrest of inspiration. This gives a gro.ss ap- 

 pearance of marbling as in lung plague, only in this case the 

 inflated interlobular tissue is dark colored in.stead of white as in 

 lung plague, and it collapses at once when incised. 



The encephalon, medulla and nerves present more or less 

 hyperaemia and even exudation. 



