IV CULTURE BY SUBCUTANEOUS INOCULATION 37 



the liver is also congested ; the spleen is not enlarged, 

 but dark ; the peritoneum, the kidneys, and the supra- 

 renals are much congested. The peritoneum is 

 moist, and there is sometimes a small amount of 

 exudation ; petechiae are often noticed in the 

 omentum. The heart's blood, and particularly the 

 lungs, contain the microbes in large numbers (Fig. 

 17). Cover-glass specimens and cultivations of the 

 blood, and particularly of the lung juice, show the 

 microbes in very large numbers. So also the peri- 

 toneum, especially the serous covering of the liver. 

 In the heart's blood' the microbes occur as single or 

 dumb-bell oval bodies, and as rods; they are either 

 in the plasma or they are contained within the 

 white blood -cells — in the latter case the cells are 

 very much swollen up, and some are disintegrating. 

 In Fig. 17 this condition is well shown. 



[The intracellular occurrence of the bacilli in the 

 guinea-pig, and, as will be mentioned presently, also 

 in the ammer, does not indicate that there is going 

 on a process of combat on the part of the cells as 

 against bacilli, as is only too readily assumed by 

 those who with Metschnikoff assume this to be 

 the case wherever cells are met with that enclose 

 bacilli ; for in our cases we are dealing with a dis- 

 ease which is rapidly fatal, and in which the bacilli 

 abound in the blood. J 



