CHAPTER, VII 



GENERAL CONSIDERATIONS 



We have shown in the preceding account that in 

 the grouse dead of the disease there occurs con- 

 stantly in the diseased lungs and liver a species of 

 bacilli in a definite distribution; that this species 

 grown on and in various media shows definite char- 

 acters ; and that with the cultures of the bacilli a 

 definite acute fatal disease is produced in mice and 

 guinea-pigs, in buntings, yellow-ammers, and spar- 

 rows ; that the disease thus produced in the bunt- 

 ings and other birds, in its pathological appearances, 

 compares in a remarkable degree with the disease 

 found in the grouse ; and that, further, the disease in 

 the bunting can be set up, not only by subcutaneous 

 inoculation, but also can be communicated directly 

 from a bird ill with the disease to a healthy bird ; 

 and that, lastly, in the animals infected with cultures 

 of the bacilli, these latter are found again in definite 

 distribution. All these facts justify us in saying 

 that this species of microbe occurring in the diseased 



