204: PARASITOLOGY. 
till it increases to twenty; later there is developed 
around this spherical mass a limiting membrane; as 
the development progresses the protoplasm sepa- 
rates from the cell wall; it then divides into two, then 
into four bodies called sporoblasts; each sporoblast 
divides into two corpuscles. Each of the corpuscles, 
under favorable conditions, becomes an amoeboid 
individual, capable of invading epithelial cells. 
Animals Infested—The ox, sheep, goat, pig, rabbit 
and man. 
Parts Infested —Epithelial cells of the intestinal 
mucous membrane and liver cells. 
Name of Disease —Coccidiosis. When the liver cells 
are invaded it causes coccidian hepatitis. When 
the intestinal. epithelial cells are invaded it causes 
intestinal coccidiosis. 
Condition Produced—When the intestinal mucosa is 
infested there is a fetid diarrhoea, an elevation of 
temperature, loss of appetite, weakness, followed by 
death. On autopsy there is found a thickened, red- 
dened mucous membrane with ulcerated patches; the 
mesenteric lymph glands are enlarged. If the liver 
is infested, small, round abscesses, varying in size to 
a hazel nut, are observed; these abscesses are filled 
with a thick, creamy or cheesy pus ; the wall is thick 
and:.the inner surface velvety in appearance; often 
the liver is several times its normal size, thoroughly 
studded with small abscesses. The carcass will be 
in an emaciated condition. 
Cocemvernr BIGEMINUM, Variety Canis (Bis—twice) 
(Canis—dog). 
~- Synonyms.—Tetrasporous Coccidia ; Cystosperm- 
ium Villarum Intestinalium Canis. 
