120 TBE SPECIFIC PBECIPITINS. 



rabbits a serum which precipitated the blood serum obtained from 

 man, also albuminous urine from man, and did not precipitate the 

 blood serum of the horse, sheep or ox. He states, however, that 

 the reaction is not wholly a specific one, inasmuch as the serum ob- 

 tained in this case gave marked cloudiness with blood sera obtained 

 from three different species of ape. 



Wassermann and Schiitze' tested serum obtained from rabbits 

 treated with human blood on 23 kinds of blood, and found that 

 none of these reacted except blood from man and from a baboon ; 

 however, the reaction with the blood of the baboon was not nearly 

 so marked as that with the blood of man. 



Dieudonn6 * treated rabbits with human blood serum, albuminous 

 urine, and pleuritic exudate. The rabbits treated with human blood 

 serum furnished a serum which gave a precipitum with human blood 

 and had no effect on the blood of the rabbit, the guinea-pig, the 

 pigeon or the goose. The animals treated with albuminous urine 

 gave a precipitum in the albuminous urine of man and had no effect 

 upon the normal urine of man or that of the rabbit. The serum ob- 

 tained from animals treated with human pleuritic exudate gave no 

 reaction with a similar exudate obtained from a guinea-pig. The 

 serum obtained from the rabbits treated with human blood serum 

 gave a precipitum not only with human blood, but also with human 

 albuminous urine and the pleuritic and peritoneal exudates obtained 

 from man. 



Nuttall ' obtained rabbit sera by treating these animals with the 

 blood of man, dog, sheep, ox and horse. These sera were tested 

 against thirty-six kinds of blood. The serum of rabbits treated with 

 dog serum gave negative results in all cases except with the blood of 

 the dog. The serum of rabbits treated with sheep serum produced 

 a marked precipitum with sheep's blood, and a distinct, but less 

 marked, reaction with the blood of the gazelle and axis deer. All the 

 other sera and bloods remained perfectly clear, excepting that of the 

 ox, squirrel and swan, in which there was very slight cloudiness. 

 The serum of the rabbits treated with ox serum produced a marked 

 precipitation only in ox serum dilutions or dried ox blood solutions, 

 but gave a distinct reaction with the blood of the gazelle and axis 

 deer. All the other bloods gave a negative reaction, a slight cloud- 

 ing only being produced in the blood serum of the sheep, gnu, 

 squirrel and swan. The serum of rabbits treated with horse serum 

 produced a precipitum only in dilutions of the horse blood or serum, 

 not even clouding other bloods. The serum of the rabbits treated 

 with human blood serum and pleuritic exudate produced a marked 

 precipitum only in human blood solutions, but the blood of four spe- 



^ Berliner Uin. Wochemchrifi, 1901. 

 ' Miinchener med. Wochentchrifl, 1901. 

 ' Journal of Hygiene, 1. 



