Acquired Modifications Heritable? 115 



of alcohol. Numerous pairs of guinea-pigs were 

 subjected to the alcohol, some for brief periods, 

 others for long periods. At the same time 

 other pairs of guinea-pigs from the same litters 

 were kept under normal conditions. It was 

 found that the guinea-pigs that were more or 

 less confirmed drunkards gave birth to a larger 

 number of young than normal pigs, but a high 

 proportion of these young were born dead. A 

 much higher percentage of them died in early 

 life than did the offspring of the normal pigs, 

 a great many of them were born deformed, and 

 many were prone to serious nervous diseases, 

 such as epileptic seizures. Furthermore, it was 

 found that such results followed more commonly 

 when the father was an inebriate than when 

 the mother was addicted to alcohol, if parents 

 were used one of whom was exposed to the 

 influence of the alcohol and the other was 

 normal. Another interesting result followed 

 from the matings of the offspring of inebriate 

 parents when the young so mated were not 

 themselves habituated to the alcohol. The 

 young produced showed the deleterious effects 



