300 DADD'S VETERINARY MEDICINE AND SURGERY. 
was cffered by Government to Professor Papa, and many persuna 
having affected animals were requested to permit their inspection. 
and, indeed, threatened with a fine if they did not. Papa saw 
about three hundred horses and mules affected. The disease ap- 
peared in circular patches of furfuraceous scales, with grayish- 
white scabs. These patches had usually well-defined margins, 
about the size of a dollar or five-shilling piece. Usually they 
were isolated, but at other times they were confluent, or running 
together in yroups. The head, neck, withers, shoulders, and loins 
were the parts chiefly affected. More rarely the upper portion of 
the extremities, and never on the lower part of the limbs, chest, 
or belly. The malady commences with a violent itching, and an 
eruption in small circumscribed points, about the size of a lentil, 
is witnessed, The scabs form, with the exudation drying and 
entangling cuticle and hairs. In the vicinity of the first, other 
eruptive spots appeared, which, widening, became confluent ana 
run into one another, especially where the skin is folded and ani- 
mals have a chance of rubbing themselves. A scab forms on the 
sore surface, and the surface beneath it is red and tumefied, but in 
a little time desquamation occurs. A very careful microscopical 
examination failed to indicate the existence of any acari. 
The disease is contagious, and Papa says all those who come 
more or less in contact with herpetic horses or mules, and espe- 
cially the conductors of the same, were covered on the arms, legs, 
chest, and face with pruriginous eruptions, limited and circum- 
scribed, sometimes isolated, occasionally confluent, in the form 
of red patches covered with papule and vesicles, which become 
incrusted with brownish-yellow scabs, beneath which purulent 
deposits formed. In consequence of the violent pruritis attending 
this disease, it was believed to be scabies or itch by the people, 
and, though in many houses individuals were affected, they were 
ashamed to confess it, and it was with great difficulty that Papa 
collected information on the subject; but, having gained confidence 
om the latter, the people more freely related their cases to him. 
The first to be affected were those intrusted with dressing the dis- 
eased animals. The parts first attacked were the articular regions 
about the forearm, arm, face, and rarely the lower limbs. 
Papa describes one of many cases of direct contagion. It a» 
curred in a lad of sixteen, who had jumped on the bare back of an 
affected horse, to take it toa watering-place. Two days afterward, 
