AORSE MANAGEMENT, ETC. 407 
of operation most likely to be successful, I shall now proceed tc 
state the result of four cases in which I have operated, and which, 
I think, I may look upon as having been followed with entire 
success, In three of the cases the patients had been bled a short 
time previous to my having seen them, and were so much weak- 
ened that they could scarcely walk. In the fourth case, a drastic 
purgative had been administered, causing superpurgation and great 
prostration of strength. In each of the four cases, the condition 
of the patient was so similar that the description I have already 
given may answer forall. Having selected a healthy young horse 
from which to obtain the blood to be transferred, I opened the 
jugular vein in the patient and in the healthy subject; and hav- 
ing iuserted the tube, as before described, into the vein of the 
healthy horse. I placed the India-rubber tube in the tin trough 
containing hot water, to maintain the right temperature, and the 
other curved tube into the descending portion of the vein in the 
patient. As soon as the current from the healthy horse had com- 
pletely expelled all atmospheric air, the instrument being thus 
arranged, the blood flowed freely from the vein of one herse intn 
that of the other in an unbroken current. The average quantity 
of blood transferred in each of these cases was about three quarts. 
I observed no particular symptoms to follow from the transfusion, 
until two quarts or more had passed from the healthy to the dis 
eased subject ; but as soon as about that quantity had flowed, there 
appeared to be produced an amount of stimulation, indicated by an 
increased action of the heart; at the same time the pupils began to 
dilate, and the countenance evinced an anxious expression. My 
former experiments led me to watch with great care the progress. 
ive dilatation of the pupil, and I deemed it expedient, in each case, 
when this symptom was well developed, to compress the tube se 
us to diminish the current, and allow the transfusion to proceed 
more gradually and slowly. Occasionally I almost completely 
interrupted the current until the subsidence of this symptom, and 
I found that when about three quarts had been transfused, any 
additional quantity was followed by unpleasant symptoms, which 
indicated the necessity of stopping the operation. On removing 
the tube and closing the vein, all symptoms of irritation gradually 
subsided, and the pulse, from being rapid and irritable, became 
slower, stronger, and fuller, gradually approaching the healthy 
wandard. 
