SYMPTOMS 135 



living tissues by means of infected utensils, the use of infected 

 instruments, and insects, especially the house fly {Musca 

 domestica.) Dalrymple has called attention to the spread of 

 this disease among animals in the lower Mississippi Valley 

 by means of the horse fly {Tabanidae) . In man many cases 

 of the disease occur from the injuries or cuts made at the post- 

 mortem of anthrax animals or by the infection of skin wounds 

 while handling infected hides or wool. Malignant pustule is 

 reported to be quite common among the employes of certain 

 tanneries and upholstering establishments where hides and 

 hair imported from infected districts or countries are used. 



3. Infection through the respiratory tract. Faser, Buch- 

 ner, L,emke, and other writers have shown experimentally 

 that the disease can be produced by the inhalation of spores. 

 In man this form of infection is quite common among the wool 

 sorters. In Great Britain, where much foreign wool is handled, 

 it has been reported as causing as many as 500 deaths 

 annually. It is known as "wool-sorters' disease." 



§ 122. Symptoms. In anthrax, the symptoms vary 

 not'only in different species of animals but also in difierent 

 individuals according to the location of the disease. Again 

 there is often considerable variation when the lesions are 

 apparently the same. The most characteristic features of the 

 disease are the suddenness of the attack, the grave general 

 disturbances, high elevation of temperature, a tendency to 

 ecchymoses of the mucous membranes and local manifestations, 

 such as carbuncles and edema of the skin, digestive disturb- 

 ances, brain complications and difficult respiration. 



Anthrax has been classified according to its course as per- 

 acute, acute and subacute. It has also been divided accord- 

 ing to the site of its manifestations as anthrax with visible 

 localization and anthrax without visible localization. 



Anthrax without visible localization. This form is gener- 

 ally due to ordinary infection presumably by spores. It 

 includes the peracute, acute, and subacute. 



I. The peracute or apoplectic anthrax gives rise to 



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